Resveratrol Improves Glucose and Other Factors in Clinical Trial

    A report published in the journal evidence based complementary and alternative medicine documents a randomized, double-blind, placebo-controlled trial which determined that supplementation with resveratrol was associated with a reduction in a number of factors associated with diabetes and cardiovascular disease. The trial enrolled 66 type II diabetic men and women residing in Iran, a country that has a high prevalence of diabetes. Participants were supplemented with 1 gram resveratrol or a placebo daily for 45 days. At the study’s conclusion, subjects who received resveratrol had experienced lower systolic blood pressure, fasting blood glucose, hemoglobin A1c, insulin and insulin resistance, and demonstrated an increase in HDL cholesterol. While glucose declined by an average of 34.9 mg/dL among those who received resveratrol, subjects who received the placebo experienced an average increase of 9.89 mg/dL as well as a rise in LDL. (Evid Based Complement Alternat Med. 2013 Sep 1.)